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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYST2 All Species: 20.91
Human Site: S601 Identified Species: 32.86
UniProt: O95251 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95251 NP_008998.1 611 70642 S601 S N K T M D P S C L K W T P P
Chimpanzee Pan troglodytes XP_511869 806 91579 S796 S N K T M D P S C L K W T P P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548192 555 64081 C546 N K T M D P S C L K W T P P K
Cat Felis silvestris
Mouse Mus musculus Q5SVQ0 613 70623 S603 S N K T M D P S C L K W T P P
Rat Rattus norvegicus Q810T5 612 70496 S602 S N K T M D P S C L K W T P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026512 611 70527 S601 S N K I M D P S C L K W T P P
Frog Xenopus laevis NP_001079995 617 71123 G607 S N K A M D P G C L K W T P P
Zebra Danio Brachydanio rerio NP_997800 568 65560 S559 S K T I D P G S L K W T P P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 T532 D S K C L H W T P K D W S K R
Honey Bee Apis mellifera XP_392324 916 101344 E899 V Y K E I D P E C L K W N P F
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 Y449 L Q W R P K E Y G K K R A Q I
Sea Urchin Strong. purpuratus XP_782361 504 58083 D495 G Y G K M L I D F S Y L L S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 L436 L D V D A S K L I W T P Y K D
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 F436 L I W K P P V F T A S Q L R F
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 F497 I Q W K P P V F T A L N R T W
Conservation
Percent
Protein Identity: 100 75.8 N.A. 89.3 N.A. 99 99 N.A. N.A. 97.8 93.1 76.4 N.A. 33.7 34 30.9 39.2
Protein Similarity: 100 75.8 N.A. 89.5 N.A. 99 99 N.A. N.A. 98.5 95.9 83.4 N.A. 49.5 48.1 48.6 53.8
P-Site Identity: 100 100 N.A. 6.6 N.A. 100 100 N.A. N.A. 93.3 86.6 20 N.A. 13.3 53.3 6.6 6.6
P-Site Similarity: 100 100 N.A. 13.3 N.A. 100 100 N.A. N.A. 93.3 86.6 20 N.A. 40 60 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 36.3 31.9 31.2
Protein Similarity: N.A. N.A. N.A. 50.4 47.6 47.4
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 6.6 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 0 0 0 0 14 0 0 7 0 0 % A
% Cys: 0 0 0 7 0 0 0 7 47 0 0 0 0 0 0 % C
% Asp: 7 7 0 7 14 47 0 7 0 0 7 0 0 0 7 % D
% Glu: 0 0 0 7 0 0 7 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 14 7 0 0 0 0 0 14 % F
% Gly: 7 0 7 0 0 0 7 7 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 14 7 0 7 0 7 0 0 0 0 0 7 % I
% Lys: 0 14 54 20 0 7 7 0 0 27 54 0 0 14 20 % K
% Leu: 20 0 0 0 7 7 0 7 14 47 7 7 14 0 0 % L
% Met: 0 0 0 7 47 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 40 0 0 0 0 0 0 0 0 0 7 7 0 0 % N
% Pro: 0 0 0 0 20 27 47 0 7 0 0 7 14 60 40 % P
% Gln: 0 14 0 0 0 0 0 0 0 0 0 7 0 7 0 % Q
% Arg: 0 0 0 7 0 0 0 0 0 0 0 7 7 7 7 % R
% Ser: 47 7 0 0 0 7 7 40 0 7 7 0 7 7 0 % S
% Thr: 0 0 14 27 0 0 0 7 14 0 7 14 40 7 0 % T
% Val: 7 0 7 0 0 0 14 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 20 0 0 0 7 0 0 7 14 54 0 0 7 % W
% Tyr: 0 14 0 0 0 0 0 7 0 0 7 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _